Posts by: Alice Melão

News

The U.S. Food and Drug Administration has granted breakthrough therapy designation to a combination of Tecentriq (atezolizumab) and Avastin (bevacizumab) for the first-line treatment of patients with advanced or metastatic hepatocellular ... Read more

July 11, 2018July 11, 2018

FDA Grants Priority Review to Keytruda-Chemo Combo for Metastatic NSCLC

News

The U.S. Food and Drug Administration (FDA) has agreed to review a combination of Keytruda (pembrolizumab) and chemotherapy as first-line treatment for metastatic squamous non-small cell lung cancer (NSCLC). Merck’s supplemental ... Read more

July 6, 2018

NBTXR3 for Soft Tissue Sarcoma May ‘Change Standard of Care,’ Researcher Says

News

Patients with soft tissue sarcoma who receive NBTXR3 in addition to standard radiation therapy have complete responses twice as often as those receiving radiation therapy alone, a Phase 2/3 clinical trial shows. ... Read more

July 3, 2018July 3, 2018

FDA Approves Phase 2 Trial Testing AIVITA’s Vaccine for Aggressive Brain Cancer

News

AIVITA Biomedical is launching a Phase 2 trial to assess the safety and effectiveness of its cell-based immunotherapy for the treatment of an aggressive form of brain cancer, called glioblastoma multiforme. This ... Read more

May 30, 2018May 30, 2018

1st Patient Treated in Phase 1 Trial of FS118, Potential Immunotherapy for Advanced Cancers

News

A Phase 1 trial testing FS118 – F-star‘s antibody designed to target two immune checkpoint proteins – in solid and advanced cancers has dosed a first patient, the company announced. The ... Read more

May 29, 2018May 29, 2018

First Lung Cancer Patient Treated with NEO-PV-01 Vaccine in Phase 1 Trial

News

Neon Therapeutics has dosed the first lung cancer patient with its investigational vaccine NEO-PV-01, in combination with the checkpoint inhibitor Keytruda (pembrolizumab) and chemotherapy, in a Phase 1b clinical trial. Specifically, ... Read more

May 22, 2018

Phase 1 Trial on Treos’ Potential Colorectal Cancer Vaccine Doses First Patient

News

A Phase 1 trial evaluating the investigational colorectal cancer vaccine PolyPEPI 1018 in patients whose disease has metastasized has begun dosing participants, Treos Bio announced. The trial (NCT03391232), which is still recruiting, is ... Read more

April 16, 2018April 16, 2018

First Stage of Bemcentinib-Keytruda Phase 2 Trial for Lung Cancer Completes Patient Enrollment

News

The first part of a Phase 2 trial investigating the AXL inhibitor bemcentinib in combination with Keytruda (pembrolizumab) in advanced non-small cell lung cancer (NSCLC) patients has completed enrollment of the planned 22 ... Read more

March 21, 2018March 21, 2018

Investigational T-Cell Therapy Promising in First Liposarcoma Patients in Phase 1/2 Trial

News

NY-ESO SPEAR T-cells, an investigational therapy by Adaptimmune Therapeutics, showed promise as a treatment for myxoid/round cell liposarcoma (MRCLS) in the first four patients in an ongoing Phase 1/2 clinical trial. ... Read more

March 2, 2018October 22, 2018

Advanced NSCLC Patients Again Being Enrolled in Phase 3 Trial of Tedopi

News

A Phase 3 trial assessing the ability of Tedopi to treat people with advanced non-small cell lung cancer (NSCLC) who failed to respond to prior therapy can again enroll patients — ... Read more