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July 13, 2018July 13, 2018

BL-8040, Plus Chemo, Extends Survival in Relapsed/Refractory Leukemia Patients, Phase 2 Trial Shows

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Treatment with investigational BL-8040 combined with a high dose of chemotherapy medication cytarabine prolonged the survival of patients with relapsed or refractory acute myeloid leukemia (AML), results from BioLineRx’s Phase 2a ... Read more

July 11, 2018July 11, 2018

FDA Grants Priority Review to Keytruda-Chemo Combo for Metastatic NSCLC

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The U.S. Food and Drug Administration (FDA) has agreed to review a combination of Keytruda (pembrolizumab) and chemotherapy as first-line treatment for metastatic squamous non-small cell lung cancer (NSCLC). Merck’s ... Read more

July 10, 2018July 10, 2018

Study Will Test CAR T-cell Immunotherapy in Young People with Brain, Spinal Cord Tumors

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The Seattle Children’s Hospital is conducting a pioneering clinical trial testing engineered immune cells as a treatment for children and young adults with a kind of brain cancer that produces ... Read more

July 6, 2018

NBTXR3 for Soft Tissue Sarcoma May ‘Change Standard of Care,’ Researcher Says

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Patients with soft tissue sarcoma who receive NBTXR3 in addition to standard radiation therapy have complete responses twice as often as those receiving radiation therapy alone, a Phase 2/3 clinical trial ... Read more

July 3, 2018July 3, 2018

FDA Approves Phase 2 Trial Testing AIVITA’s Vaccine for Aggressive Brain Cancer

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AIVITA Biomedical is launching a Phase 2 trial to assess the safety and effectiveness of its cell-based immunotherapy for the treatment of an aggressive form of brain cancer, called glioblastoma multiforme. ... Read more

June 29, 2018June 29, 2018

Combination of Immune Cells Improves Chances of Successful Immunotherapy

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Immunotherapy with checkpoint inhibitors is more effective in cancer patients who have elevated numbers of specific types of immune cells inside their tumors, a study suggests. Patients with a favorable ... Read more

June 27, 2018June 27, 2018

DNA Vaccine To Be Tested in Advanced Colorectal Cancer Patients for 1st Time in Phase 1/2 Trial

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Researchers in Australia are testing for a first time the safety and efficacy of a DNA-based vaccine to treat advanced colorectal cancer in people with this disease, after promising results ... Read more

June 26, 2018June 26, 2018

Gene Editing of Healthy Cells Improves CAR T-cell Therapy for AML, Preclinical Study Shows

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Genetic modification of healthy blood stem cells prevents off-target effects of chimeric antigen receptor (CAR) T-cell therapy for treating acute myeloid leukemia (AML), a recent preclinical study shows. The study, ... Read more

June 22, 2018

First Cancer Patient Dosed in Trial Investigating Immunotherapy ADXS-NEO

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The first patient has been dosed in a Phase 1 clinical trial testing ADXS-NEO, a potential cancer immunotherapy designed to activate immune system responses against the unique mutations in ... Read more

June 20, 2018

Older Melanoma Patients Respond Better to Anti-PD-1 Immunotherapies, Study Shows

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Older melanoma patients respond better to the anti-PD-1 immunotherapy Keytruda (pembrolizumab), according to new data from a multinational study. Researchers are attributing these differences to a reduced immunosuppressive tumor environment ... Read more

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