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March 5, 2020March 5, 2020

Video: BioNews’ Social Media Campaign Highlights #WhatMakesMeRare

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In recognition of Rare Disease Day Feb. 29, BioNews Services launched a social media campaign last month asking patients to describe what makes them rare. Running Feb. 7–29, the ... Read more

March 4, 2020March 23, 2020

Early Data Support Agenus’ 2 Lead Immunotherapies for Advanced Cervical Cancer

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Agenus announced early data supporting its two lead immunotherapy candidates — balstilimab and zalifrelimab — for the second-line treatment of advanced cervical cancer that responded poorly to platinum chemotherapy. ... Read more

March 2, 2020March 2, 2020

Researchers Develop Safer CAR T-cell That Can Be Temporarily Turned ‘Off’

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Researchers have developed a potentially safer CAR T-cell product — one with a “safety switch” — that can be deactivated in the presence of specific molecules, a new study ... Read more

February 26, 2020March 23, 2020

First Patient Enrolled in Phase 1 Trial Investigating Galinpepimut-S and Opdivo for MPM

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Investigators enrolled the first patient in a Phase 1 clinical trial to evaluate the effects of the cancer vaccine galinpepimut-S in combination with immune checkpoint inhibitor Opdivo (nivolumab) as ... Read more

February 24, 2020March 5, 2020

FDA Grants Priority Review to Lurbinectedin for Small Cell Lung Cancer

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The U.S. Food and Drug Administration (FDA) accepted an application from PharmaMar and Jazz Pharmaceuticals asking for the accelerated approval of lurbinectedin to treat patients with small cell lung ... Read more

February 21, 2020February 21, 2020

Opdivo-Yervoy Combo Showing Durable Benefits in Untreated Kidney Cancers in Long-term Trial

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A combination of two immune checkpoint inhibitors, Opdivo (nivolumab) and Yervoy (ipilimumab), continues to significantly extend the lives of people newly diagnosed with advanced renal cell carcinoma (RCC) compared ... Read more

February 19, 2020February 19, 2020

Potential CAR T-cell Therapy Targeting ROR1 Seen to Clear Cancer in Leukemia Mouse Model

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A potential new CAR T-cell therapy by Oncternal Therapeutics showed strong activity against leukemia in mice, completely eliminating cancer cells from major “tissue reservoirs” in four weeks and extending survival ... Read more

February 17, 2020February 17, 2020

Opdivo Extends Survival in Pretreated Advanced Stomach Cancer Patients, Phase 3 Trial Results Show

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The immune checkpoint inhibitor Opdivo (nivolumab) may be a safe and effective treatment for people with advanced gastric or esophagogastric junction cancer who failed standard chemotherapy regimens, results from a Phase ... Read more

February 14, 2020February 14, 2020

Ilixadencel Improves Responses, Extends Survival in Newly-diagnosed Metastatic Kidney Cancer, Trial Results Show

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Adding Immunicum‘s ilixadencel to standard surgical and medical treatment for newly-diagnosed metastatic renal cell carcinoma — the most common form of kidney cancer — increases patient responses, duration of response, and ... Read more

February 12, 2020February 12, 2020

Pepinemab-Bavencio Combo Shows Positive Anti-Tumor Activity in Advanced Lung Cancer, Phase 1/2 Trial Shows

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A combination of Vaccinex‘s investigational antibody pepinemab and the immune checkpoint inhibitor Bavencio (avelumab) was well-tolerated and showed signs of lasting anti-tumor activity in patients with advanced non-small cell lung ... Read more

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