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July 25, 2018July 25, 2018

FDA Expedites Tecentriq-Avastin Combo for Most Common Liver Cancer

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The U.S. Food and Drug Administration has granted breakthrough therapy designation to a combination of Tecentriq (atezolizumab) and Avastin (bevacizumab) for the first-line treatment of patients with advanced or metastatic ... Read more

July 24, 2018July 24, 2018

Activating Brain’s Reward System Reduces Tumor Size in Mice, Study Reports

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Activation of the brain’s reward system reduced the size of tumors in mice, according to a study suggesting that a positive mental state may be beneficial in the anti-cancer ... Read more

July 20, 2018July 20, 2018

Immunotherapy Use Can Double Survival Rate of Melanoma Patients with Brain Metastasis, Large Study Reports

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Melanoma patients with brain metastasis have seen significant improvements in their survival rates since immune checkpoint inhibitors like Yervoy (ipilimumab) came into treatment use, a study based on “real-life” ... Read more

July 18, 2018July 18, 2018

Survival Benefits of Checkpoint Inhibitors 2-times Higher in Men with Advanced Cancers Than Women, Study Finds

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Men with advanced cancers respond much better than women do to treatment with anti-PD-1 or anti-CTLA-4 immune checkpoint inhibitors, a pooled analysis of multiple clinical trial results found. Future research ... Read more

July 17, 2018July 17, 2018

‘Backpacks’ for T-cells Boost Immune Responses Against Tumors, Mouse Study Shows

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Attaching “backpacks” carrying immune-stimulating molecules to T-cells effectively enhances their activity, a study found. The approach can be used in any kind of tumor-fighting T-cell, including engineered cells, and ... Read more

July 13, 2018July 13, 2018

BL-8040, Plus Chemo, Extends Survival in Relapsed/Refractory Leukemia Patients, Phase 2 Trial Shows

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Treatment with investigational BL-8040 combined with a high dose of chemotherapy medication cytarabine prolonged the survival of patients with relapsed or refractory acute myeloid leukemia (AML), results from BioLineRx’s Phase 2a ... Read more

July 11, 2018July 11, 2018

FDA Grants Priority Review to Keytruda-Chemo Combo for Metastatic NSCLC

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The U.S. Food and Drug Administration (FDA) has agreed to review a combination of Keytruda (pembrolizumab) and chemotherapy as first-line treatment for metastatic squamous non-small cell lung cancer (NSCLC). Merck’s ... Read more

July 10, 2018July 10, 2018

Study Will Test CAR T-cell Immunotherapy in Young People with Brain, Spinal Cord Tumors

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The Seattle Children’s Hospital is conducting a pioneering clinical trial testing engineered immune cells as a treatment for children and young adults with a kind of brain cancer that produces ... Read more

July 6, 2018

NBTXR3 for Soft Tissue Sarcoma May ‘Change Standard of Care,’ Researcher Says

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Patients with soft tissue sarcoma who receive NBTXR3 in addition to standard radiation therapy have complete responses twice as often as those receiving radiation therapy alone, a Phase 2/3 clinical trial ... Read more

July 3, 2018July 3, 2018

FDA Approves Phase 2 Trial Testing AIVITA’s Vaccine for Aggressive Brain Cancer

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AIVITA Biomedical is launching a Phase 2 trial to assess the safety and effectiveness of its cell-based immunotherapy for the treatment of an aggressive form of brain cancer, called glioblastoma multiforme. ... Read more

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