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November 16, 2018November 16, 2018

Yervoy-Opdivo Combo Improves Response Rates in Advanced Bladder Cancer, Trial Data Show

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Combining Yervoy (ipilimumab) with Opdivo (nivolumab) appears to lengthen survival and trigger a stronger response against tumors than Opdivo alone in patients with metastatic bladder cancer who were already treated with ... Read more

November 14, 2018November 14, 2018

FDA Approves Keytruda for Liver Cancer Patients Who Had Received Nexavar

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The U.S. Food and Drug Administration (FDA) has approved Keytruda (pembrolizumab) as a treatment for patients with hepatocellular carcinoma (HCC) — the most common type of liver cancer — who previously had ... Read more

November 13, 2018November 13, 2018

FDA Approves Keytruda-Chemotherapy Combo as First-line Therapy for NSCLC

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Keytruda (pembrolizumab) can now be used in combination with chemotherapy — Paraplatin (carboplatin) plus Taxol (paclitaxel) or Abraxane (nab-paclitaxel) — as first-line therapy for patients with metastatic squamous non-small cell lung cancer (NSCLC) ... Read more

November 9, 2018November 9, 2018

Keytruda Elicits Complete Response in 40% of Group of High-risk Bladder Cancer Patients, Early Phase 2 Trial Data Show

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The immune checkpoint inhibitor Keytruda (pembrolizumab) completely eliminated tumors in almost 40% of a group of bladder cancer patients in an ongoing Phase 2 trial, Merck (known as MSD outside ... Read more

November 7, 2018November 7, 2018

CHMP Favors EU Approval of Keytruda for Advanced Melanoma Patients with Complete Tumor Resection

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The Committee for Medicinal Products for Human Use (CHMP), an arm of the European Medicines Agency (EMA), has recommended the approval of Keytruda (pembrolizumab) for the treatment of advanced melanoma patients ... Read more

November 6, 2018November 6, 2018

SQZ Biotech and Roche Expand Collaboration to Develop Cell Therapies for Cancer Patients

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SQZ Biotech and Roche are expanding their collaboration to jointly develop and market cancer treatments based on antigen-presenting cells (APCs). According to SQZ, the partnership combines the expertise of SQZ ... Read more

November 2, 2018November 2, 2018

Keytruda-Inlyta Combo Extends Survival in Advanced Renal Cell Carcinoma Patients, Phase 3 Trial Shows

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A combination of Keytruda (pembrolizumab) and Inlyta (axitinib) significantly extended the lives of patients with advanced renal cell carcinoma (RCC) and delayed disease progression or death, according to a Phase 3 clinical trial. ... Read more

October 31, 2018October 31, 2018

Immunotherapy Particularly Effective Against Aggressive Hereditary Melanoma, Study Reports

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Patients with hereditary melanoma associated with mutations in the CDKN2A gene respond well to immunotherapy, possible due to an increased mutational load in these tumors, a study suggests. The study, ... Read more

October 30, 2018October 30, 2018

Opdivo Fails to Extend Survival in SCLC Patients in Phase 3 Trial, Bristol-Myers Squibbs Reports

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Bristol-Myers Squibb‘s immune checkpoint inhibitor Opdivo (nivolumab) is no better than standard chemotherapy at extending the lives of patients with small cell lung cancer (SCLC) who failed prior platinum-based chemotherapy, ... Read more

October 26, 2018

Opdivo-Yervoy Combo Shows Potential as First-line Treatment for Certain Colorectal Cancers

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A combination of Bristol-Myers Squibb‘s Opdivo (nivolumab) and low-dose Yervoy (ipilimumab) induced promising and durable response rates in metastatic colorectal cancer patients with certain genetic abnormalities who had not received prior ... Read more