News

April 4, 2017

Opdivo-Avastin Combo Holds Promise as Metastatic Renal Cell Carcinoma Therapy

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Combining Opdivo (nivolumab) with the anti-VEGF drug Avastin (bevacizumab) may be a promising treatment approach for patients with metastatic renal cell carcinoma (mRCC), according to data from a Phase 1 ... Read more

April 3, 2017April 3, 2017

How IDH Protein Mutations Help Cancerous Brain Tumors Evade Immunotherapy

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Mutations of the isocitrate dehydrogenase (IDH) protein help the cancerous version of a brain tumor known as a glioma evade therapies that involve revving up the immune system, a study ... Read more

March 31, 2017

Non-mutation-based Cancer Gene Expression Is Promising Therapy Path, Professor Says

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A better understanding of how cancer cells control their gene expression to turn on tumor-promoting pathways could help scientists identify vulnerabilities in the process that could lead to therapies. A professor ... Read more

March 30, 2017March 30, 2017

FDA Approves Bavencio to Treat Rare Form of Metastatic Skin Cancer

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Adults and children older than 12 years old with metastatic Merkel cell carcinoma (MCC) will now have access to the anti-PD-L1 immunotherapy Bavencio (avelumab) in the United States. It is ... Read more

March 29, 2017March 29, 2017

CHMP Recommends Opdivo Be Approved in EU to Treat Head and Neck Squamous Cell Cancer

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The Committee for Medicinal Products for Human Use (CHMP), part of the European Medicines Agency, has issued a positive opinion that recommends Opdivo (nivolumab) be approved to treat people with squamous cell ... Read more

March 28, 2017

Chronix Blood Test Can Predict Cancer Patients’ Response to Immunotherapy, Study Shows

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A blood-based cancer test has shown promise in predicting how solid-cancer patients will respond to immunotherapy, according to the test’s developer, Chronix Biomedical. The study, “Tumor Cell-Free DNA Copy Number Instability ... Read more

March 27, 2017March 27, 2017

Experimental Immunotherapy Offers Hope for Children with Brain Cancer

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A new type of immunotherapy was highly effective against five types of childhood brain cancer when tested in mice. The treatment, which is already in clinical trials for other cancer ... Read more

March 23, 2017March 23, 2017

Vedantra Collaborates with Neon to Develop Cancer Vaccines

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Vedantra Pharmaceuticals and Neon Therapeutics have entered an immuno-oncology collaboration to explore cancer vaccine research. The purpose of the partnership is to continue the research and development of cancer vaccines that ... Read more

March 22, 2017March 22, 2017

FDA Names Potential Merkel Cell Therapy, Using aNK Cells, an Orphan Drug

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The U.S Food and Drug Administration has granted orphan drug status to NantKwest‘s activated natural killer (aNK) cell therapy for the treatment of advanced Merkel cell carcinoma. The designation is offered ... Read more

March 21, 2017March 21, 2017

Trial Aimed at Helping Bladder Cancer Patients Choose Immunotherapy or Surgery

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Patients with bladder cancer often have to choose between surgical removal of their bladder or a three-year course of the immunotherapy Bacillus Calmette-Guérin (BCG), which most people know as the ... Read more