Posts by: Marta Figueiredo

News

Patients with hereditary melanoma associated with mutations in the CDKN2A gene respond well to immunotherapy, possible due to an increased mutational load in these tumors, a study suggests. The ... Read more

October 24, 2018

Keytruda Improves Survival in Patients with Relapsed or Metastatic Head, Neck Cancer, Interim Data Show

News

First-line treatment with Keytruda (pembrolizumab) — alone or in combination with standard chemotherapy — significantly prolongs survival of patients with recurrent or metastatic head and neck squamous cell carcinoma (HNSCC), ... Read more

August 17, 2018August 17, 2018

Cancer Cells Can Flood Bloodstream with Protein ‘Warriors’ Against Immune Response, Study Finds

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Cancer cells release into the bloodstream small vesicles armed with PD-1 ligand (PD-L1) — a protein that suppresses the activation of cancer-fighting immune cells — so as to mute ... Read more

June 26, 2018June 26, 2018

Gene Editing of Healthy Cells Improves CAR T-cell Therapy for AML, Preclinical Study Shows

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Genetic modification of healthy blood stem cells prevents off-target effects of chimeric antigen receptor (CAR) T-cell therapy for treating acute myeloid leukemia (AML), a recent preclinical study shows. The study, ... Read more

April 17, 2018

Immunotherapy Combo Boosts Survival in Mouse Models of Mesothelioma, Study Finds

News

A combination of two immunotherapies — VIC-008 and Mozobil (plerixafor, or AMD3100) — suppresses mesothelioma growth and prolongs survival, suggesting a potential therapy for this type of cancer, a ... Read more

April 11, 2018April 11, 2018

Keytruda-Epacadostat Combo Fails Primary Goal in Phase 3 Trial for Melanoma, Companies Announce

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A Phase 3 clinical trial evaluating a combination of Keytruda and epacadostat in metastatic melanoma patients will be stopped after the combo failed the study’s first primary goal, Incyte Corporation and Merck announced. ... Read more

April 10, 2018

Newly Developed Molecule Boosts Anti-cancer Immunity, Mouse Study Shows

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A new version of a known molecule is highly effective in stimulating pro-inflammatory and anti-tumor responses in humans, a recent mouse study revealed. These findings, along with the technology used ... Read more

March 23, 2018March 23, 2018

Tecentriq Combination Shows Positive Interim Results for Untreated Advanced Lung Cancer in Phase 3 Trial

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Tecentriq (atezolizumab) in combination with chemotherapy reduces the risk of disease progression or death in people with previously untreated advanced squamous non-small cell lung cancer (NSCLC), according to interim data from ... Read more

March 20, 2018March 20, 2018

UCLA Uses Magnetic Fields to Deliver Gene Therapy-carrying Nanospears to Cells

News

UCLA researchers have developed what they call nanospears to deliver molecules such as genes into selected cells with pinpoint accuracy. The new method, which uses magnetic fields to deliver the ... Read more

March 14, 2018March 14, 2018

New Type of CAR T-cells Offers Hope for ‘First Viable’ Treatment of T-cell Blood Cancers, Study Reports

News

A new approach using genetically modified T-cells may become the first clinically viable, targeted immunotherapy for T-cell blood cancers, a preclinical study reports. The study, “An “off-the-shelf” fratricide-resistant CAR-T ... Read more

Posts by: Marta Figueiredo

Marta Figueiredo

Immunotherapy Particularly Effective Against Aggressive Hereditary Melanoma, Study Reports

Keytruda Improves Survival in Patients with Relapsed or Metastatic Head, Neck Cancer, Interim Data Show

Cancer Cells Can Flood Bloodstream with Protein ‘Warriors’ Against Immune Response, Study Finds

Gene Editing of Healthy Cells Improves CAR T-cell Therapy for AML, Preclinical Study Shows

Immunotherapy Combo Boosts Survival in Mouse Models of Mesothelioma, Study Finds

Keytruda-Epacadostat Combo Fails Primary Goal in Phase 3 Trial for Melanoma, Companies Announce

Newly Developed Molecule Boosts Anti-cancer Immunity, Mouse Study Shows

Tecentriq Combination Shows Positive Interim Results for Untreated Advanced Lung Cancer in Phase 3 Trial

UCLA Uses Magnetic Fields to Deliver Gene Therapy-carrying Nanospears to Cells

New Type of CAR T-cells Offers Hope for ‘First Viable’ Treatment of T-cell Blood Cancers, Study Reports

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