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September 7, 2018September 7, 2018

Affimed and Genentech Partner to Develop Immunotherapies Against Cancer Based on Natural Killer Cells

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A recent collaboration between Affimed and Genentech, a member of the Roche group, aims to develop immunotherapies — called engager-based immunotherapies — that aim to establish a bridge between a patient’s own immune cells and cancer ... Read more

September 5, 2018

New UNC Software Aims to Make Stem Cell Transplants Safer for Leukemia Patients

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New computer software is able to identify targets for potential immunotherapies in individual leukemia patients undergoing stem cell transplants, a new study shows. These results open the door for tailored and ... Read more

September 4, 2018

Adlai Nortye Opens Boston Site to Advance Cancer Treatments

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Adlai Nortye has opened its first U.S. innovation center, in Boston, Massachusetts. The China-based company is dedicated to the development of treatments for metabolic diseases and cancer. The Boston staff’s ... Read more

August 30, 2018August 31, 2018

Blocking Cellular Pathway May Make Radiotherapy More Effective by Activating Immune System, Early Study Reports

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Targeting a specific cellular pathway may improve the effectiveness of radiotherapy given to cancer patients by activating the immune system, according to a study in mice. The research, “Non-canonical NF-κB Antagonizes ... Read more

August 30, 2018August 30, 2018

Mutations in MUC16 Gene May Help Define Immunotherapy Strategies for Gastric Cancer, Study Suggests

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Mutations in the MUC16 gene may help predict disease outcome and provide treatment guidance for gastric cancer patients, researchers suggest. These mutations are also linked to a higher mutational burden, which ... Read more

August 28, 2018August 28, 2018

New Scoring System May Help Predict Patient Response to Checkpoint Inhibitors, Study Reports

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A newly developed scoring system could help identify melanoma patients who may benefit the most from treatment with a type of immunotherapy known as a checkpoint inhibitor, a study finds. The ... Read more

August 24, 2018August 24, 2018

High Nitrogen Levels Can Increase Cancer Cell Growth, But Also Enhance Immunotherapy Response, Study Suggests

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While dysregulation of the urea cycle gives a growth advantage to cancer cells, it also makes them more amenable to immunotherapy, a study reports. The study, “Urea Cycle Dysregulation Generates ... Read more

August 23, 2018August 23, 2018

Genprex, MD Anderson to Explore Oncoprex-Immunotherapies Combo in Broad Array of Cancers

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Genprex has entered a sponsored research agreement with The University of Texas MD Anderson Cancer Center to further explore its investigational therapeutic candidate Oncoprex. The company will provide $2 million ... Read more

August 21, 2018September 20, 2018

FDA Approves Opdivo for Certain Patients with Advanced Small Cell Lung Cancer

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The U.S. Food and Drug Administration has approved Opdivo (nivolumab) to treat patients with metastatic small cell lung cancer (SCLC) who failed to respond to platinum-based chemotherapy and at least one other ... Read more

August 21, 2018August 21, 2018

Blocking Protein Known as YAP May Boost Ability of Immunotherapies to Fight Cancer, Study Suggests

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Blocking a protein known for regulating organ size and favoring tumor growth – called YAP – could boost anti-cancer responses and increase the effectiveness of immunotherapies, a new study in ... Read more